The Toyota Sequoia is a Full-size SUV manufactured by Toyota and derived from its Tundra pickup truck.

Introduced in 2000 and manufactured at Toyota Motor Manufacturing Indiana in Princeton, Indiana, the Sequoia is the first vehicle from a Japanese marque in the popular mainstream full-sized SUV class in North America, and initial planning done by first-generation Sequoia chief engineer Kaoru Hosegawa aimed the Sequoia directly at the Ford Expedition, also competing with the Chevrolet Tahoe and the later Nissan Armada.